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Meta-Analysis
. 2015;11(10):1519-30.
doi: 10.2217/fon.15.43.

Surgery for liver metastases from breast cancer

Petros Charalampoudis  1 , Dimitrios Mantas, Georgios C Sotiropoulos, Dimitrios Dimitroulis, Gregory Kouraklis, Christos Markopoulos
Affiliations
Meta-Analysis

Surgery for liver metastases from breast cancer

Petros Charalampoudis et al. Future Oncol. 2015.

Abstract

Introduction: Liver metastases from breast cancer (BCLM) confer poor survival. Liver resection in BCLM patients has been increasingly employed.

Aim: We undertook a systematic review to evaluate the role of hepatic resection in patients with breast cancer metastatic to the liver.

Materials & methods: In total, 36 studies were overviewed. Patient populations, characteristics, morbidity, mortality and survival were documented.

Results: Median overall survival was 41 months. Major morbidity was rare while 30-day postoperative mortality was near nil.

Conclusion: Liver surgery for BCLM can be performed with low mortality, acceptable morbidity and promising survival benefit in carefully selected patients.

Keywords: breast cancer; chemotherapy; hepatectomy; liver metastases; metastasectomy; resection; surgery; survival.

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