Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Nov;80(5):474-8.
doi: 10.1111/j.1600-0447.1989.tb03008.x.

Serum dopamine-beta-hydroxylase activity in clinical subtypes of depression

M K Sapru  1 , B S Rao, S M Channabasavanna
Affiliations

Serum dopamine-beta-hydroxylase activity in clinical subtypes of depression

M K Sapru et al. Acta Psychiatr Scand. 1989 Nov.

Abstract

Serum dopamine-beta-hydroxylase (DBH) activity was determined in male adult psychiatric patients (n = 280) and age-matched male healthy controls (n = 100). Patients included in the study had no history of previous or current exposure to psychoactive drugs and were diagnosed according to Research Diagnostic Criteria. A significant decrease in serum DBH activity was noted in patients with psychotic major depressive disorder (n = 50) as compared with controls. In acute schizophrenics (n = 100), nonpsychotic major depressives (n = 45) and patients with manic disorder (n = 85), mean DBH activity did not differ significantly from the control values.

PubMed Disclaimer

Comment in

Substances