Lumbar puncture refusal in sub-Saharan Africa: A call for further understanding and intervention

Affiliations

¹ From the Division of Neuroinfectious Diseases and Neuroimmunology, Department of Neurology (K.T.T.), Johns Hopkins Hospital, Baltimore, MD; the Department of Internal Medicine (K.M., L.H., V.K., M.A., O.K.S.), University of Zambia School of Medicine, Lusaka, Zambia; the Department of Internal Medicine (L.H.), University of Maryland School of Medicine, Baltimore, MD; the Department of Pediatrics and Child Health, College of Medicine (M.M.), and the Department of Internal Medicine (J.M.), Queen Elizabeth Central Hospital, Blantyre, Malawi; the Neurology Unit, Department of Internal Medicine (E.O.N.), Federal Medical Center Owerri, Imo State, Nigeria; the Neurology Unit (T.L.), Department of Internal Medicine, Lagos University Teaching Hospital, Lagos State, Nigeria; the Neurology Unit, Department of Internal Medicine (C.B.M.), Jos University Teaching Hospital, Jos, Plateau State, Nigeria; the Division of Infectious Diseases & International Medicine, Department of Medicine (D.R.B.), University of Minnesota, Minneapolis; Epilepsy Division, Department of Neurology (G.L.B.), University of Rochester, NY; the Chikankata Epilepsy Care Team (G.L.B.), Mazabuka, Zambia; and the Global Neurology Program, Division of Neuroimmunology, Center for Virology and Vaccine Research, Department of Neurology (O.K.S.), Beth Israel Deaconess Medical Center, Boston, MA. kthakur1@jhmi.edu.
² From the Division of Neuroinfectious Diseases and Neuroimmunology, Department of Neurology (K.T.T.), Johns Hopkins Hospital, Baltimore, MD; the Department of Internal Medicine (K.M., L.H., V.K., M.A., O.K.S.), University of Zambia School of Medicine, Lusaka, Zambia; the Department of Internal Medicine (L.H.), University of Maryland School of Medicine, Baltimore, MD; the Department of Pediatrics and Child Health, College of Medicine (M.M.), and the Department of Internal Medicine (J.M.), Queen Elizabeth Central Hospital, Blantyre, Malawi; the Neurology Unit, Department of Internal Medicine (E.O.N.), Federal Medical Center Owerri, Imo State, Nigeria; the Neurology Unit (T.L.), Department of Internal Medicine, Lagos University Teaching Hospital, Lagos State, Nigeria; the Neurology Unit, Department of Internal Medicine (C.B.M.), Jos University Teaching Hospital, Jos, Plateau State, Nigeria; the Division of Infectious Diseases & International Medicine, Department of Medicine (D.R.B.), University of Minnesota, Minneapolis; Epilepsy Division, Department of Neurology (G.L.B.), University of Rochester, NY; the Chikankata Epilepsy Care Team (G.L.B.), Mazabuka, Zambia; and the Global Neurology Program, Division of Neuroimmunology, Center for Virology and Vaccine Research, Department of Neurology (O.K.S.), Beth Israel Deaconess Medical Center, Boston, MA.

PMID: 25964478
PMCID: PMC4433455
DOI: 10.1212/WNL.0000000000001561

Lumbar puncture refusal in sub-Saharan Africa: A call for further understanding and intervention

Kiran T Thakur et al. Neurology. 2015.

. 2015 May 12;84(19):1988-90.

doi: 10.1212/WNL.0000000000001561.

Affiliations

¹ From the Division of Neuroinfectious Diseases and Neuroimmunology, Department of Neurology (K.T.T.), Johns Hopkins Hospital, Baltimore, MD; the Department of Internal Medicine (K.M., L.H., V.K., M.A., O.K.S.), University of Zambia School of Medicine, Lusaka, Zambia; the Department of Internal Medicine (L.H.), University of Maryland School of Medicine, Baltimore, MD; the Department of Pediatrics and Child Health, College of Medicine (M.M.), and the Department of Internal Medicine (J.M.), Queen Elizabeth Central Hospital, Blantyre, Malawi; the Neurology Unit, Department of Internal Medicine (E.O.N.), Federal Medical Center Owerri, Imo State, Nigeria; the Neurology Unit (T.L.), Department of Internal Medicine, Lagos University Teaching Hospital, Lagos State, Nigeria; the Neurology Unit, Department of Internal Medicine (C.B.M.), Jos University Teaching Hospital, Jos, Plateau State, Nigeria; the Division of Infectious Diseases & International Medicine, Department of Medicine (D.R.B.), University of Minnesota, Minneapolis; Epilepsy Division, Department of Neurology (G.L.B.), University of Rochester, NY; the Chikankata Epilepsy Care Team (G.L.B.), Mazabuka, Zambia; and the Global Neurology Program, Division of Neuroimmunology, Center for Virology and Vaccine Research, Department of Neurology (O.K.S.), Beth Israel Deaconess Medical Center, Boston, MA. kthakur1@jhmi.edu.
² From the Division of Neuroinfectious Diseases and Neuroimmunology, Department of Neurology (K.T.T.), Johns Hopkins Hospital, Baltimore, MD; the Department of Internal Medicine (K.M., L.H., V.K., M.A., O.K.S.), University of Zambia School of Medicine, Lusaka, Zambia; the Department of Internal Medicine (L.H.), University of Maryland School of Medicine, Baltimore, MD; the Department of Pediatrics and Child Health, College of Medicine (M.M.), and the Department of Internal Medicine (J.M.), Queen Elizabeth Central Hospital, Blantyre, Malawi; the Neurology Unit, Department of Internal Medicine (E.O.N.), Federal Medical Center Owerri, Imo State, Nigeria; the Neurology Unit (T.L.), Department of Internal Medicine, Lagos University Teaching Hospital, Lagos State, Nigeria; the Neurology Unit, Department of Internal Medicine (C.B.M.), Jos University Teaching Hospital, Jos, Plateau State, Nigeria; the Division of Infectious Diseases & International Medicine, Department of Medicine (D.R.B.), University of Minnesota, Minneapolis; Epilepsy Division, Department of Neurology (G.L.B.), University of Rochester, NY; the Chikankata Epilepsy Care Team (G.L.B.), Mazabuka, Zambia; and the Global Neurology Program, Division of Neuroimmunology, Center for Virology and Vaccine Research, Department of Neurology (O.K.S.), Beth Israel Deaconess Medical Center, Boston, MA.

PMID: 25964478
PMCID: PMC4433455
DOI: 10.1212/WNL.0000000000001561

No abstract available

PubMed Disclaimer

Figures

**Figure. Visual poster used in the Cryptococcal Optimal Antiretroviral Therapy Timing (COAT) trial for patient education regarding lumbar punctures**
Created by Kosuke Yasukawa. Reprinted with permission.

See this image and copyright information in PMC

References

1. Wynter WE. Four cases of tubercular meningitis in which paracentesis of the theca vertebralis was performed for the relief of fluid pressure. Lancet 1891;1:981–982.
1. Bicanic T, Brouwer AE, Meintjes G, et al. Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures. AIDS 2009;23:701–706. - PubMed
1. Boulware DR, Meya DB, Muzoora C, et al. Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis. N Engl J Med 2014;370:2487–2498. - PMC - PubMed
1. English M, Esamai F, Wasunna A, et al. Assessment of inpatient paediatric care in first referral level hospitals in 13 districts in Kenya. Lancet 2004;363:1948–1953. - PubMed
1. Korein J, Cravioto H, Leicach M. Reevaluation of lumbar puncture: a study of 129 patients with papilledema or intracranial hypertension. Neurology 1959;9:290–297. - PubMed

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Medical
- MedlinePlus Health Information
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Lumbar puncture refusal in sub-Saharan Africa: A call for further understanding and intervention

Affiliations

Lumbar puncture refusal in sub-Saharan Africa: A call for further understanding and intervention

Authors

Affiliations

Figures

References

MeSH terms

LinkOut - more resources

Full Text Sources

Medical

Miscellaneous