Versatile Electrochemical C-H Amination via Zincke Intermediates

Abstract

Simply by applying electricity, the amination reaction of a broad variety of arenes, heteroarenes, and benzylic substrates is achieved. Pyridine serves as the nitrogen source and the intermediate cationic species are well-protected from over-oxidation.

Keywords: amination; electrochemistry; oxidative coupling; sustainable chemistry; synthetic methods.