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Review
. 2015 Apr 17:37:e2015020.
doi: 10.4178/epih/e2015020. eCollection 2015.

Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance

Venkataramana Kandi  1 , Sabitha Kandi  2
Affiliations
Review

Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance

Venkataramana Kandi et al. Epidemiol Health. .

Abstract

Objectives: The emergence of multi-drug resistance among various microbial pathogens has been a cause of serious concern to the medical world, limiting the choice of antibiotics. Considering that it may take decades to synthesize new antimicrobial drugs that combat resistant pathogens, the search for alternatives to conventional antimicrobial agents has begun.

Methods: In his paper we attempted to review the physico-chemical properties of nanoparticles, their modes of action and potential use in medicine and research with special reference to antimicrobial properties.

Results: Nanomolecules and nanoparticles have in recent years been extensively studied for their utility not only as antibiotics but also as vehicles to carry antibiotics or other agents such as cancer chemotherapeutics to target sites and limit damage to host cells.

Conclusion: Nanomolecules were positively evaluated for their antimicrobial activities. Anti-biofilm activities of nanoparticles, utility of nanomaterials as carrier agents of drugs signifies their importance in medicine and research.

Keywords: Anti-bacterial agents; Nanomedicine; Nanomolecules; Nanoparticles.

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Conflict of interest statement

The authors have no conflicts of interest to declare for this study.

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References

    1. Kalaskar A, Venkataramana K. Determination of antimicrobial resistance pattern and production of extended-spectrum Β-lactamases amongst Escherichia coli and Klebsiella pneumoniae from clinical isolates. J Med Bacteriol. 2012;1:17–24.
    1. Ramana KV, Mohanty SK, Kumar A. In-vitro activities of current antimicrobial agents against isolates of pyoderma. Indian J Dermatol Venereol Leprol. 2008;74:430. - PubMed
    1. Ramana KV, Rao R. Significance of screening for colonization and vancomycin resistance in Staphylococcus aureus isolated from anterior nares of school going children. Online J Health Allied Sci. 2009;8:20.
    1. Ramana KV, Rao R, Sharada ChV, Kareem M, Reddy LR, Ratna Mani M. Modified Hodge test: a useful and the low-cost phenotypic method for detection of carbapenemase producers in Enterobacteriaceae members. J Nat Sc Biol Med. 2013;4:346–348. - PMC - PubMed
    1. Ramana KV, Kalaskar A, Rao M, Rao SD. Aetiology and antimicrobial susceptibility patterns of lower respiratory tract infections (LRTI’s) in a rural tertiary care teaching hospital in Karimnagar, South India. Am J Infect Dis Microbiol. 2013;1:101–105.

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