Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 May 12:2015:bcr2014207841.
doi: 10.1136/bcr-2014-207841.

Preservation of fertility in non-Peutz-Jegher syndrome-associated ovarian sex cord tumour with annular tubules

Affiliations
Case Reports

Preservation of fertility in non-Peutz-Jegher syndrome-associated ovarian sex cord tumour with annular tubules

Kyriaki Chatziioannidou et al. BMJ Case Rep. .

Abstract

We report the successful conservative management of a non-Peutz-Jegher syndrome-associated ovarian sex cord tumour with annular tubules in a 32-year-old patient. The patient underwent a unilateral salpingo-oophorectomy by laparoscopy, and conceived spontaneously approximately 6 months after the diagnosis. After a normal term pregnancy, she underwent a contralateral laparoscopic salpingo-oophorectomy with hysterectomy. The patient is now on hormone replacement therapy and, after 30 months of follow-up, continues to present no sign of disease recurrence.

PubMed Disclaimer

Figures

Figure 1
Figure 1
MRI findings. The lesion appears as a solid hypointense mass in the axial T1-weighted image (white arrow in A); as hypointense with rare hyperintense spots in the axial T2-weighted image (white arrow in B); with restricted diffusion as seen on b1000 images (white arrow in C); and with a low apparent diffusion coefficient (black arrow in D). Picture 1e corresponds to the fusion of T2 (B) and b1000 (C), thus combining anatomic and functional information.
Figure 2
Figure 2
Laparoscopic view of the ovarian mass.
Figure 3
Figure 3
Macroscopic view of the whole ovarian mass (left). Cross-section of the mass (right).
Figure 4
Figure 4
Microscopic view of the ovarian mass.

References

    1. Kurman JR, Carcangiu ML, Herrington CS et al. WHO classification of tumor of female reproductive organs. Lyon: IARC Press, 2014.
    1. Quirk JT, Natarajan N. Sex cord-stromal tumors of the ovary: tumors with granulosa and Sertoli–Leydig elements. Gynecol Oncol 2005;97:519–23. 10.1016/j.ygyno.2005.02.007 - DOI - PubMed
    1. Scully RE, Sobin LH. Histological typing of ovarian tumors. World Health Organization international histological classification of tumors. 2nd edn Berlin: Springer, 1999.
    1. Song SH, Lee JK, Saw HS et al. Peutz-Jeghers syndrome with multiple genital tract tumors and breast cancer: a case report with a review of literatures. J Korean Med Sci 2006;21:752–7. 10.3346/jkms.2006.21.4.752 - DOI - PMC - PubMed
    1. Hart WR, Kumure N, Crissman JD. Ovarian neoplasms resembling sex cord tumors with annular tubules. Cancer 1980;45:2352–63. 10.1002/1097-0142(19800501)45:9<2352::AID-CNCR2820450920>3.0.CO;2-# - DOI - PubMed

Publication types