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. 2015 May;6(3):360-6.
doi: 10.1111/jdi.12309. Epub 2014 Dec 11.

Association between sugar-sweetened beverages and type 2 diabetes: A meta-analysis

Meng Wang  1 , Min Yu  1 , Le Fang  1 , Ru-Ying Hu  1
Affiliations

Association between sugar-sweetened beverages and type 2 diabetes: A meta-analysis

Meng Wang et al. J Diabetes Investig. 2015 May.

Abstract

Aims/introduction: Many studies have been carried out to examine the association between sugar-sweetened beverages and the incident of type 2 diabetes, but results are mixed. The aim of the present study was to estimate the association between sugar-sweetened beverage intake and the risk of type 2 diabetes.

Materials and methods: PubMed, Springer Link and Elsevier databases were searched up to July 2014. Prospective studies published on the association between sugar-sweetened beverage intake and the risk of type 2 diabetes were included. The pooled relative risks (RRs) and 95% confidence intervals (CIs) for highest versus lowest category of sugar-sweetened beverages were estimated using a random-effects model.

Results: The pooled effect estimate of sugar-sweetened beverage intake was 1.30 (95% confidence interval [CI] 1.21-1.39) for type 2 diabetes; stratified by geographic region of the studies, the pooled effect estimates were 1.34 (95% CI 0.74-2.43), 1.30 (95% CI 1.20-1.40), 1.29 (95% CI 1.09-1.53) in Asia, the USA and Europe,respectively; the pooled effect estimates were 1.26 (95% CI 1.16-1.36) with adjusting body mass index and 1.38 (95% CI 1.23-1.56) without adjusting body mass index.

Conclusions: Our findings suggested that sugar-sweetened beverage intake was associated with an increased risk of type 2 diabetes, and the association was attenuated by adjustment for body mass index. Specifically, the associations were also found to be significantly positive in the USA and Europe.

Keywords: Meta-analysis; Sugar-sweetened beverages; Type 2 diabetes.

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Figures

Figure 1
Figure 1
Process of study selection
Figure 2
Figure 2
Relative risk (RR) for type 2 diabetes for highest versus lowest intake of sugar-sweetened beverages. CI, confidence interval.
Figure 3
Figure 3
The results of subgroup analysis by geographic region of studies (0, Asia; 1, the USA; 2, Europe). CI, confidence interval; RR, relative risk.
Figure 4
Figure 4
The effects of sugar-sweetened beverages on type 2 diabetes with or without adjusting body mass index (0,Yes; 1, No). CI, confidence interval; RR, relative risk.
See this image and copyright information in PMC

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