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Multicenter Study
. 2015 Jun;34(6):667-9.
doi: 10.1097/INF.0000000000000685.

Hemophagocytic lymphohistiocytosis in children with visceral leishmaniasis

Daniel Blázquez-Gamero  1 , Nerea Domínguez-Pinilla, Carmen Chicharro, Sagrario Negreira, Pilar Galán, Beatriz Pérez-Gorricho, Cristina Calvo, Luis Prieto, María De la Parte, Enrique Otheo, Jose Luis Vivanco, Jesús Ruiz-Contreras; Madrid Leishmaniasis Study Group
Collaborators, Affiliations
Multicenter Study

Hemophagocytic lymphohistiocytosis in children with visceral leishmaniasis

Daniel Blázquez-Gamero et al. Pediatr Infect Dis J. 2015 Jun.

Abstract

Acquired hemophagocytic lymphohistiocitosis (HLH) syndrome can be a complication of visceral leishmaniasis (VL). A multicenter prospective study was conducted to determine the frequency of HLH syndrome in children with VL. Twenty-four children with VL were identified, and 10 (41%) developed HLH syndrome. VL should be ruled out in all children with HLH criteria living in or coming from endemic areas.

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