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Comparative Study
. 1989 Oct 15;263(2):597-9.
doi: 10.1042/bj2630597.

Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance

B R Stevenson  1 , J M Anderson, I D Braun, M S Mooseker
Affiliations
Comparative Study

Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance

B R Stevenson et al. Biochem J. .

Abstract

A comparison was made of the phosphate content of the tight-junction-specific protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance, a parameter reflective of tight-junctional permeability. Analysis revealed that the ZO-1 from the low-resistance strain contained approximately twice as much phosphate as that from the high-resistance strain.

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