Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Jun 14;13(22):6170-4.
doi: 10.1039/c5ob00515a.

A transition-metal-free Heck-type reaction between alkenes and alkyl iodides enabled by light in water

Wenbo Liu  1 , Lu Li, Zhengwang Chen, Chao-Jun Li
Affiliations

A transition-metal-free Heck-type reaction between alkenes and alkyl iodides enabled by light in water

Wenbo Liu et al. Org Biomol Chem. .

Abstract

A transition-metal-free coupling protocol between various alkenes and non-activated alkyl iodides has been developed by using photoenergy in water for the first time. Under UV irradiation and basic aqueous conditions, various alkenes efficiently couple with a wide range of non-activated alkyl iodides. A tentative mechanism, which involves an atom transfer radical addition process, for the coupling is proposed.

PubMed Disclaimer

LinkOut - more resources