Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 May 15:8:274.
doi: 10.1186/s13071-015-0872-8.

Detection of Cyclospora in captive chimpanzees and macaques by a quantitative PCR-based mutation scanning approach

Marianna Marangi  1   2 , Anson V Koehler  3 , Sergio A Zanzani  4 , Maria T Manfredi  5 , Emanuele Brianti  6 , Annunziata Giangaspero  7 , Robin B Gasser  8
Affiliations

Detection of Cyclospora in captive chimpanzees and macaques by a quantitative PCR-based mutation scanning approach

Marianna Marangi et al. Parasit Vectors. .

Abstract

Background: Cyclospora is a protistan parasite that causes enteritis in several species of animals including humans. The aim of this study was to investigate the presence of Cyclospora in captive non-human primates.

Methods: A total of 119 faecal samples from Pan troglodytes, Macaca sylvanus, Cercopithecus cephus, Erythrocebus patas, Chlorocebus aethiops and Macaca fascicularis from a wildlife animal rescue center as well as from Macaca fascicularis from an experimental primate research center were tested for the presence of Cyclospora by quantitative real-time PCR (qPCR) and single-strand conformation polymorphism (SSCP) analysis.

Results: Cyclospora was detected in three Pan troglodytes (13.6%) and nine (9.3%) Macaca fascicularis.

Conclusions: The present study represents the first record of Cyclospora in captive primates in Europe, suggesting the presence of Cyclospora cayetanensis, which is transmissible to humans.

PubMed Disclaimer

References

    1. Fletcher M, McLaws M, Ellis J. Prevalence of gastrointestinal pathogens in developed and developing countries: systematic review and meta-analysis. J Public Health Res. 2013;2:e9. doi: 10.4081/jphr.2013.e9. - DOI - PMC - PubMed
    1. Lainson R. The genus Cyclospora (Apicomplexa: Eimeriidae), with a description of Cyclosporaschneideri n. sp. In the snake Anilius scytale scytale (Aniliidae) from Amazonian Brazil–a review. Mem Inst Oswaldo Cruz. 2005;100:103–10. - PubMed
    1. Ashford RW. Occurrence of an undescribed coccidian in man in Papua New Guinea. Ann Trop Med Parasitol. 1979;73:497–500. - PubMed
    1. Ortega YR, Sterling CR, Gilman RH, Cama VA, Diaz F. Cyclospora species–a new protozoan pathogen of humans. N Engl J Med. 1993;328:1308–12. doi: 10.1056/NEJM199305063281804. - DOI - PubMed
    1. Ortega YR, Gilman RH, Sterling CR. A new coccidian parasite (Apicomplexa: Eimeriidae) from humans. J Parasitol. 1994;80:625–9. doi: 10.2307/3283201. - DOI - PubMed

Publication types

MeSH terms