Review
doi: 10.18632/oncotarget.3671.
Deubiquitinases in cancer
Affiliations
- PMID: 25972356
- PMCID: PMC4536986
- DOI: 10.18632/oncotarget.3671
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Review
Deubiquitinases in cancer
Oncotarget.
.
Abstract
Deubiquitinases are deubiquitinating enzymes (DUBs), which remove ubiquitin from proteins, thus regulating their proteasomal degradation, localization and activity. Here, we discuss DUBs as anti-cancer drug targets.
Keywords: cancer; deubiquitinases; inhibitor; ubiquitylation.
Conflict of interest statement
The authors declare no conflict of interest.
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