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Review
. 2015 May 30;6(15):12872-89.
doi: 10.18632/oncotarget.3671.

Deubiquitinases in cancer

Rongbin Wei  1 , Xiaodong Liu  2 , Weixin Yu  3 , Tianshu Yang  1 , Wenping Cai  1 , Junjun Liu  1 , Xiao Huang  1 , Guo-tong Xu  1 , Shouliang Zhao  3 , Jianhua Yang  1 , Shangfeng Liu  3
Affiliations
Review

Deubiquitinases in cancer

Rongbin Wei et al. Oncotarget. .

Abstract

Deubiquitinases are deubiquitinating enzymes (DUBs), which remove ubiquitin from proteins, thus regulating their proteasomal degradation, localization and activity. Here, we discuss DUBs as anti-cancer drug targets.

Keywords: cancer; deubiquitinases; inhibitor; ubiquitylation.

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Conflict of interest statement

CONFLICTS OF INTEREST

The authors declare no conflict of interest.

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