Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2015 May 14;6(5):e1762.
doi: 10.1038/cddis.2015.133.

Stressing out the ER in aminoglycoside-induced hearing loss

Affiliations
Editorial

Stressing out the ER in aminoglycoside-induced hearing loss

P Garcia-Huerta et al. Cell Death Dis. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Models of aminoglycoside-induced ototoxicity. (a) Aminoglycosides activate the UPR system in cell culture. (b) Cochlear explant treated with geneticin undergoes ER stress. (c) XBP1 haploinsufficiency (XBP1+/−) specifically affects SGCs density and synaptic connections (synaptic ribbons)

Comment on

References

    1. Chen LF, Kaye D. Med Clin North Am 2011; 95: 819–842. - PubMed
    1. Grohskopf LA et alPediatr Infect Dis J 2005; 24: 766–773. - PubMed
    1. Huth ME et alOtolaryngol 2011; 2011: 937861. - PubMed
    1. Gillespie PG, Walker RG. Nature 2001; 413: 194–202. - PubMed
    1. Francis SP et alJ Neurosci 2013; 33: 3079–3093. - PMC - PubMed