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Review
. 2015 Sep 1;36(33):2212-8.
doi: 10.1093/eurheartj/ehv164. Epub 2015 May 13.

The perils of surrogate endpoints

William S Weintraub  1 , Thomas F Lüscher  2 , Stuart Pocock  3
Affiliations
Review

The perils of surrogate endpoints

William S Weintraub et al. Eur Heart J. .
No abstract available

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Figures

Figure 1
Figure 1
Conceptual model of the various possible relationships between a potential surrogate and a clinical endpoint. Only (A) is a true surrogate. See text for explanation of the panels. Reprinted with permission from Elsevier (The Lancet 2010;376:1673).
Figure 2
Figure 2
The relationship between low-density lipoprotein lowering and cardiovascular events in 26 clinical trials of statins.
See this image and copyright information in PMC

References

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