Initiating oral anti diabetic drug: alternatives to metformin
- PMID: 25976586
Initiating oral anti diabetic drug: alternatives to metformin
Abstract
While most published articles on oral anti diabetic therapy approve of metformin, few discuss what should be done if metformin is contraindicated or not tolerated. This article defines metformin intolerance, and discusses various pharmacological options available for persons with type 2 diabetes who cannot take metformin and do not accept/require insulin.
Keywords: Metformin intolerance, type 2 diabetes, sulfonylureas, alpha glucosidase inhibitors, pioglitazone, SGLT2 inhibitors, DPP4 inhibitors..
Similar articles
-
Oral combination therapy in primary care.J Pak Med Assoc. 2015 May;65(5):574-5. J Pak Med Assoc. 2015. PMID: 26028398
-
Direct comparison among oral hypoglycemic agents and their association with insulin resistance evaluated by euglycemic hyperinsulinemic clamp: the 60's study.Metabolism. 2009 Aug;58(8):1059-66. doi: 10.1016/j.metabol.2009.03.007. Epub 2009 Jun 18. Metabolism. 2009. PMID: 19394976 Clinical Trial.
-
Oral antihyperglycemic treatment options for type 2 diabetes mellitus.Med Clin North Am. 2015 Jan;99(1):87-106. doi: 10.1016/j.mcna.2014.08.012. Epub 2014 Oct 18. Med Clin North Am. 2015. PMID: 25456645 Review.
-
[Therapies for newly-onset diabetic patients].Nihon Rinsho. 2005 Feb;63 Suppl 2:525-32. Nihon Rinsho. 2005. PMID: 15779435 Review. Japanese. No abstract available.
-
Lispro insulin and metformin versus other combination in the diabetes mellitus type 2 management after secondary oral antidiabetic drug failure.Coll Antropol. 2003 Jun;27(1):181-7. Coll Antropol. 2003. PMID: 12974145 Clinical Trial.
Cited by
-
Sleeve gastrectomy to treat concomitant polycystyc ovary syndrome, insulin and leptin resistance in a 27-years morbidly obese woman unresponsive to insulin-sensitizing drugs: A 3-year follow-up.Int J Surg Case Rep. 2015;17:36-8. doi: 10.1016/j.ijscr.2015.10.015. Epub 2015 Oct 21. Int J Surg Case Rep. 2015. PMID: 26520034 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Medical
Miscellaneous