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Review
. 2015:2015:925640.
doi: 10.1155/2015/925640. Epub 2015 Apr 21.

Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway

Arshad H Rahmani  1 , Fahad M Al Shabrmi  1 , Khaled S Allemailem  1 , Salah M Aly  2 , Masood A Khan  3
Affiliations
Review

Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway

Arshad H Rahmani et al. Biomed Res Int. 2015.

Abstract

Green tea is commonly used as a beverage worldwide, especially in China, Japan, Morocco, and Saudi Arabia. Green tea and its constituents have been considered very effective in the prevention and treatment of various diseases. It contains a variety of catechins, which show a pivotal role in the modulation of biological activities and also act as chemopreventive agents. Earlier studies have confirmed that green tea and its chief constituent epigallocatechin gallate (EGCG) have a potential role in the management of cancer through the modulation of cell signaling pathways. In this review, we focused on the beneficial effects of green tea and its constituents in the cancer prevention and treatment and its impact on modulation of molecular pathways.

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Figures

Figure 1
Figure 1
Active constituents of green tea.
Figure 2
Figure 2
Role of green tea in cancer prevention through the modulation of genes involved in initiations, promotion, and progression of cancer.
Figure 3
Figure 3
Green tea modulates the various cell signalling pathways in cancer.
See this image and copyright information in PMC

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