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Comment
. 2015 Jun 2;112(22):E2849-50.
doi: 10.1073/pnas.1505017112. Epub 2015 May 15.

Reanalysis of 3,707 novel human microRNA candidates

Christina Backes  1 , Andreas Keller  2
Affiliations
Comment

Reanalysis of 3,707 novel human microRNA candidates

Christina Backes et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Example of miRNA precursor derived from two initially different precursors shifted by 62 bases. The upper left shows the left precursor with two mature forms and the typical hairpin structure. The right half shows the second precursor also with two mature forms and the typical hairpin structure. The 3′ and 5′ forms of the first and second precursor are almost identical. Below, the image the sequence of the two precursors are highlighted, as well as the merged form.
Fig. 2.
Fig. 2.
Structure of the merged miRNA precursor from Fig. 1 with the two mature forms colored in red and blue, calculated by RNAFold (rna.tbi.univie.ac.at/cgi-bin/RNAfold.cgi).
See this image and copyright information in PMC

Comment in

Comment on

  • Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs.
    Londin E, Loher P, Telonis AG, Quann K, Clark P, Jing Y, Hatzimichael E, Kirino Y, Honda S, Lally M, Ramratnam B, Comstock CE, Knudsen KE, Gomella L, Spaeth GL, Hark L, Katz LJ, Witkiewicz A, Rostami A, Jimenez SA, Hollingsworth MA, Yeh JJ, Shaw CA, McKenzie SE, Bray P, Nelson PT, Zupo S, Van Roosbroeck K, Keating MJ, Calin GA, Yeo C, Jimbo M, Cozzitorto J, Brody JR, Delgrosso K, Mattick JS, Fortina P, Rigoutsos I. Londin E, et al. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1106-15. doi: 10.1073/pnas.1420955112. Epub 2015 Feb 23. Proc Natl Acad Sci U S A. 2015. PMID: 25713380 Free PMC article.

References

    1. Londin E, et al. Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs. Proc Natl Acad Sci USA. 2015;112(10):E1106–E1115. - PMC - PubMed

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