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Review
. 2015 May;40(2):97-103.
doi: 10.5395/rde.2015.40.2.97. Epub 2014 Dec 9.

Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies

Dohyun Kim  1 , Euiseong Kim  1
Affiliations
Review

Antimicrobial effect of calcium hydroxide as an intracanal medicament in root canal treatment: a literature review - Part II. in vivo studies

Dohyun Kim et al. Restor Dent Endod. 2015 May.

Abstract

The first part of this study reviewed the characteristics of calcium hydroxide (Ca(OH)2) and summarized the results of in vitro studies related to its antimicrobial effects. The second part of this review covers in vivo studies including human clinical studies and animal studies. The use of Ca(OH)2 as an intracanal medicament represented better histological results in animal studies. However, human clinical studies showed limited antimicrobial effects that microorganisms were reduced but not eliminated through the treatment, and that some species had resistance to Ca(OH)2. Most of clinical outcome studies supported that there is no improvement in healing of periapical lesions when Ca(OH)2 was applied between appointments. Further studies are required for the antimicrobial effects of Ca(OH)2, and search for the ideal material and technique to completely clean infected root canals should be continued.

Keywords: Antimicrobial effect; Calcium hydroxide; Endodontics; Intracanal medicament; Microorganism.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

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