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Comment
. 2015 Jul;23(7):387-8.
doi: 10.1016/j.tim.2015.05.003. Epub 2015 May 15.

How Ebola has been evolving in West Africa

Si-Qing Liu  1 , Simon Rayner  1 , Bo Zhang  2
Affiliations
Comment

How Ebola has been evolving in West Africa

Si-Qing Liu et al. Trends Microbiol. 2015 Jul.

Abstract

The ongoing Ebola outbreak in West Africa has generated fears of a global epidemic. Particularly, estimates of higher substitution rates have raised concerns about increased transmissibility or virulence. A recent study using a more comprehensive datasets demonstrates lower variation, highlighting the importance of representative datasets and limitations of computational modelling.

Keywords: Ebola; West Africa; evolution; low variation; nucleotide substitutions rate.

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  • Virology. Mutation rate and genotype variation of Ebola virus from Mali case sequences.
    Hoenen T, Safronetz D, Groseth A, Wollenberg KR, Koita OA, Diarra B, Fall IS, Haidara FC, Diallo F, Sanogo M, Sarro YS, Kone A, Togo AC, Traore A, Kodio M, Dosseh A, Rosenke K, de Wit E, Feldmann F, Ebihara H, Munster VJ, Zoon KC, Feldmann H, Sow S. Hoenen T, et al. Science. 2015 Apr 3;348(6230):117-9. doi: 10.1126/science.aaa5646. Epub 2015 Mar 26. Science. 2015. PMID: 25814067 Free PMC article.

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