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. 2015 May;15(5):329-32.
doi: 10.1089/vbz.2014.1760.

Orthobunyavirus antibodies among humans in selected parts of the Rift Valley and northeastern Kenya

Collins Odhiambo  1   2   3 , Marietjie Venter  2   4 , Robert Swanepoel  2 , Rosemary Sang  1   3
Affiliations

Orthobunyavirus antibodies among humans in selected parts of the Rift Valley and northeastern Kenya

Collins Odhiambo et al. Vector Borne Zoonotic Dis. 2015 May.

Abstract

Ngari, Bunyamwera, Ilesha, and Germiston viruses are among the mosquito-borne human pathogens in the Orthobunyavirus genus, family Bunyaviridae, associated with febrile illness. Although the four orthobunyaviruses have been isolated from mosquito and/or tick vectors sampled from different geographic regions in Kenya, little is known of human exposure in such areas. We conducted a serologic investigation to determine whether orthobunyaviruses commonly infect humans in Kenya. Orthobunyavirus-specific antibodies were detected by plaque reduction neutralization tests in 89 (25.8%) of 345 persons tested. Multivariable analysis revealed age and residence in northeastern Kenya as risk factors. Implementation of acute febrile illness surveillance in northeastern Kenya will help to detect such infections.

Keywords: Arboviruses; Bunyaviridae; Kenya; Orthobunyavirus.

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Conflict of interest statement

Author Disclosure Statement

No conflicting financial interests exist.

The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the Centers for Disease Control and Prevention or the institutions with which the authors are affiliated

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