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Comment
. 2015 May 19;42(5):785-7.
doi: 10.1016/j.immuni.2015.04.020.

Krüppel-ling of IRF4-Dependent DCs into Two Functionally Distinct DC Subsets

Sammy Bedoui  1 , William R Heath  2
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Comment

Krüppel-ling of IRF4-Dependent DCs into Two Functionally Distinct DC Subsets

Sammy Bedoui et al. Immunity. .
Free article

Abstract

IRF4-dependent DCs have been associated with induction of both Th1 and Th17 cells. In this issue of Immunity, Tussiwand et al. (2015) demonstrate that a dependence on KLF4 identifies a subset of IRF4-dependent DC that preferentially promotes Th2 cell differentiation.

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