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Case Reports
. 2015 Jan-Mar;13(1):103-5.
doi: 10.1590/S1679-45082015RC2907. Epub 2015 Mar 3.

Storiform collagenoma: case report

[Article in English, Portuguese]
Guilherme Flosi Stocchero  1
Affiliations
Case Reports

Storiform collagenoma: case report

[Article in English, Portuguese]
Guilherme Flosi Stocchero. Einstein (Sao Paulo). 2015 Jan-Mar.

Abstract
in English, Portuguese

Storiform collagenoma is a rare tumor, which originates from the proliferation of fibroblasts that show increased production of type-I collagen. It is usually found in the face, neck and extremities, but it can also appear in the trunk, scalp and, less frequently, in the oral mucosa and the nail bed. It affects both sexes, with a slight female predominance. It may be solitary or multiple, the latter being an important marker for Cowden syndrome. It presents as a painless, solid nodular tumor that is slow-growing. It must be considered in the differential diagnosis of other well-circumscribed skin lesions, such as dermatofibroma, pleomorphic fibroma, sclerotic lipoma, fibrolipoma, giant cell collagenoma, benign fibrous histiocytoma, intradermal Spitz nevus and giant cell angiohistiocytoma.

O colagenoma estoriforme é um tumor raro originado a partir da proliferação de fibroblastos com produção aumentada de colágeno tipo I. É encontrado mais frequentemente na face, pescoço e extremidades, podendo aparecer no tronco, couro cabeludo e, raramente, na mucosa oral e leito subungueal. Afeta ambos os gêneros, com discreta predominância em mulheres. Pode ser solitário ou múltiplo, sendo que, neste caso, é um importante indicador da presença de síndrome de Cowden. Apresenta-se como tumor sólido, nodular, de crescimento lento e indolor. Deve constar como diagnóstico diferencial de tumores cutâneos bem delimitados, como dermatofibroma, fibroma pleomórfico, lipoma esclerótico, fibrolipoma, colagenoma de células gigantes, histiocitoma fibroso benigno, nevo de Spitz intradérmico e angioistiocitoma de células gigantes.

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Figures

Figure 1
Figure 1. Aspect of the injury before surgery
Figure 2
Figure 2. Aspect of operated site (2 months) after surgery
Figura 1
Figura 1. Aspecto pré-operatório da lesão
Figura 2
Figura 2. Aspecto pós-operatório (2 meses) do sítio de exérese da lesão
See this image and copyright information in PMC

References

    1. Rapini RP, Golitz LE. Sclerotic fibromas of the skin. J Am Acad Dermatol. 1989;20(2 Pt 1):266–271. - PubMed
    1. Lee JH, An JS, Lee ES, Kwon SY, Kim YS. Comparison of sporadic sclerotic fibroma and solitary fibrous tumor in the oral cavity. Yonsei Med J. 2007;48(3):535–539. - PMC - PubMed
    1. Tosti A, Cameli N, Peluso AM, Fanti PA, Peserico A. Storiform collagenoma of the nail. Cutis. 1999;64(3):203–204. - PubMed
    1. Requena L, Gutiérrez J, Sánchez Yus E. Multiple sclerotic fibromas of the skin. A cutaneous marker of Cowden’s disease. J Cutan Pathol. 1992;19(4):346–351. Review. - PubMed
    1. Izquierdo MJ, Pastor MA, Carrasco L, Requena C, Soguero ML, Moreno C, et al. Sclerotic fibroma with multinucleated giant cells. Actas Dermosifiliogr. 2001;92(9):419–421. Spanish.

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