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Meta-Analysis
. 2015 May 21;2015(5):CD011277.
doi: 10.1002/14651858.CD011277.pub2.

Alginate dressings for treating pressure ulcers

Jo C Dumville  1 , Samantha J Keogh, Zhenmi Liu, Nikki Stubbs, Rachel M Walker, Mathew Fortnam
Affiliations
Meta-Analysis

Alginate dressings for treating pressure ulcers

Jo C Dumville et al. Cochrane Database Syst Rev. .

Abstract

Background: Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. Dressings are widely used to treat pressure ulcers and there are many options to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use for the treatment of pressure ulcers. This review is part of a suite of Cochrane reviews investigating the use of dressings in the treatment of pressure ulcers. Each review will focus on a particular dressing type.

Objectives: To assess the effects of alginate dressings for treating pressure ulcers in any care setting.

Search methods: For this review, in April 2015 we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication.

Selection criteria: Published or unpublished randomised controlled trials (RCTs) comparing the effects of alginate with alternative wound dressings or no dressing in the treatment of pressure ulcers (stage II or above).

Data collection and analysis: Two review authors independently performed study selection, risk of bias assessment and data extraction.

Main results: We included six studies (336 participants) in this review; all studies had two arms. The included studies compared alginate dressings with six other interventions that included: hydrocolloid dressings, silver containing alginate dressings, and radiant heat therapy. Each of the six comparisons included just one study and these had limited participant numbers and short follow-up times. All the evidence was of low or very low quality. Where data were available there was no evidence of a difference between alginate dressings and alternative treatments in terms of complete wound healing or adverse events.

Authors' conclusions: The relative effects of alginate dressings compared with alternative treatments are unclear. The existing trials are small, of short duration and at risk of bias. Decision makers may wish to consider aspects such as cost of dressings and the wound management properties offered by each dressing type, for example, exudate management.

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Conflict of interest statement

Jo C Dumville: nothing to declare. Samantha Keogh: nothing to declare. Nikki Stubbs has received funding from pharmaceutical companies to support training and education events in the NHS where she works and payments have been received by the author for non product‐related educational sessions. These have been unrelated to the subject matter of the systematic review and have never been in support or in pursuit of the promotion of products. Rachel Walker: is currently employed by the National Health and Medical Research Council's Centre of Research Excellence in Nursing (NCREN), Griffith University Australia. Skin integrity including pressure ulcers is a research focus of NCREN. Matthew Fortnam: nothing to declare. Zhenmi Liu: nothing to declare

This protocol/review is part of a suite of reviews investigating the use of individual dressing types in the treatment of pressure ulcers. The first review in this suite was developed by co‐author Samantha Keogh. The objective of undertaking these reviews is to use them in an overview which draws together all existing Cochrane review evidence regarding the use of dressing treatments for pressure ulcers to guide clinician decision‐making.

Figures

1
1
Study flow diagram.
2
2
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
3
3
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
See this image and copyright information in PMC

Comment in

References

References to studies included in this review

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