Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jan;3(1):13-21.
doi: 10.1159/000366231.

Hemodynamic changes and baroreflex sensitivity associated with carotid endarterectomy and carotid artery stenting

Qinqin Cao  1 , Jun Zhang  1 , Gelin Xu  1
Affiliations
Review

Hemodynamic changes and baroreflex sensitivity associated with carotid endarterectomy and carotid artery stenting

Qinqin Cao et al. Interv Neurol. 2015 Jan.

Abstract

Atherosclerotic carotid lesion is a major cause of stroke which accounts for up to 20% of ischemic stroke. Aggressive treatment of carotid stenosis may prevent stroke. Currently, carotid endarterectomy (CEA) and carotid artery stenting (CAS) are the first-line treatments for severe carotid stenosis. CEA is superior to medical therapy in preventing stroke and cardiovascular death. CAS has emerged as an alternative to CEA in recent years due to its less invasive nature. However, both CEA and CAS may be associated with adverse hemodynamic changes as well as a variation of carotid baroreflex sensitivity. There is no consensus on which of these two methods is more advantageous concerning the procedure-related hemodynamic changes. This article reviews the hemodynamic changes and baroreflex sensitivity after CEA and CAS.

Keywords: Baroreflex sensitivity; Carotid artery stenting; Carotid endarterectomy; Hemodynamic changes.

PubMed Disclaimer

References

    1. Wong JH, Findlay JM, Suarez-Almazor ME. Hemodynamic instability after carotid endarterectomy: risk factors and associations with operative complications. Neurosurgery. 1997;41:35–43. - PubMed
    1. Dangas G, et al. Postprocedural hypotension after carotid artery stent placement: predictors and short- and long-term clinical outcomes. Radiology. 2000;215:677–683. - PubMed
    1. Schreihofer AM, Guyenet PG. The baroreflex and beyond: control of sympathetic vasomotor tone by GABAergic neurons in the ventrolateral medulla. Clin Exp Pharmacol Physiol. 2002;29:514–521. - PubMed
    1. Aicher SA, et al. Anatomical substrates for baroreflex sympathoinhibition in the rat. Brain Res Bull. 2000;51:107–110. - PubMed
    1. Palkovits M. New York: Raven Press; 1981. Neuropeptides and biogenic amines in central cardiovascular control mechanisms; in Buckley JP Ferario CM (eds): Central Nervous System Mechanisms in Hypertension; pp. 73–87.

LinkOut - more resources