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Review
. 2015 Aug;205(2):W141-9.
doi: 10.2214/AJR.14.13457. Epub 2015 May 22.

Spectrum of Physiologic and Pathologic Skeletal Muscle (18)F-FDG Uptake on PET/CT

Sellam Karunanithi  1 , Ramya Soundararajan  1 , Punit Sharma  1 , Niraj Naswa  1 , Chandrasekhar Bal  1 , Rakesh Kumar  1
Affiliations
Review

Spectrum of Physiologic and Pathologic Skeletal Muscle (18)F-FDG Uptake on PET/CT

Sellam Karunanithi et al. AJR Am J Roentgenol. 2015 Aug.

Abstract

Objective: Skeletal muscle (18)F-FDG uptake on PET/CT can be either physiologic or related to a variety of different pathologic conditions. FDG PET/CT can be used for assessment of primary and metastatic tumors and infective or inflammatory conditions affecting the musculature.

Conclusion: In this article, we describe the various causes and patterns of skeletal muscle FDG uptake. Familiarity with these patterns is essential for proper interpretation of clinical FDG PET/CT images.

Keywords: 18F-FDG; PET/CT; metastasis; rhabdomyosarcoma; skeletal muscle.

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