GDF11 and the Mythical Fountain of Youth
- PMID: 26003784
- DOI: 10.1016/j.cmet.2015.05.009
GDF11 and the Mythical Fountain of Youth
Abstract
Identifying candidates that rejuvenate aged muscle stem cells is an important strategy toward developing therapies to treat age-related diseases. In this issue, Egerman et al. (2015) re-investigate the activity of GDF11 in myogenesis, recently suggested as an anti-aging agent, and instead find a potent inhibitory effect on skeletal muscle regeneration.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.Cell Metab. 2015 Jul 7;22(1):164-74. doi: 10.1016/j.cmet.2015.05.010. Epub 2015 May 19. Cell Metab. 2015. PMID: 26001423 Free PMC article.
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