Management of gastrointestinal involvement in scleroderma
- PMID: 26005632
- PMCID: PMC4437639
- DOI: 10.1007/s40674-014-0005-0
Management of gastrointestinal involvement in scleroderma
Abstract
Gastrointestinal tract (GIT) commonly affects patients with systemic sclerosis (SSc). The GI involvement is quite heterogeneous varying from asymptomatic disease to significant dysmotility causing complications like malabsorption, weight loss and severe malnutrition. This review focuses on the management of GI involvement in SSc and has been categorized based on the segment of GIT involved. A brief discussion on the role of patient reported outcome measures in SSc-GI involvement has also been incorporated.
Keywords: Gastrointestinal tract; bacterial overgrowth; constipation; diarrhea; dysphagia; gastric antral vascular ectasia; gastroesophageal reflux; gastroparesis; intestinal dysmotility; nutrition; scleroderma; systemic sclerosis.
References
-
- Al-Dhaher FF, Pope JE, Ouimet JM. Determinants of morbidity and mortality of systemic sclerosis in Canada. Seminars in arthritis and rheumatism. 2010;39(4):269–77. - PubMed
-
- Bodukam V, Hays RD, Maranian P, Furst DE, Seibold JR, Impens A, et al. Association of gastrointestinal involvement and depressive symptoms in patients with systemic sclerosis. Rheumatology. 2011;50(2):330–4. [This reference highlights the burden of GI involvement in patients with SSc.] - PMC - PubMed
-
- Omair MA, Lee P. Effect of gastrointestinal manifestations on quality of life in 87 consecutive patients with systemic sclerosis. The Journal of rheumatology. 2012;39(5):992–6. - PubMed
-
- Butt S, Emmanuel A. Systemic sclerosis and the gut. Expert review of gastroenterology & hepatology. 2013;7(4):331–9. - PubMed
-
- Jaovisidha K, Csuka ME, Almagro UA, Soergel KH. Severe gastrointestinal involvement in systemic sclerosis: report of five cases and review of the literature. Seminars in arthritis and rheumatism. 2005;34(4):689–702. - PubMed
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources