Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Jun;36(6):1283-95.
doi: 10.1088/0967-3334/36/6/1283. Epub 2015 May 26.

Estimating a regional ventilation-perfusion index

Affiliations

Estimating a regional ventilation-perfusion index

P A Muller et al. Physiol Meas. 2015 Jun.

Abstract

This is a methods paper, where an approximation to the local ventilation-perfusion ratio is derived. This approximation, called the ventilation-perfusion index since it is not exactly the physiological ventilation-perfusion ratio, is calculated using conductivity reconstructions obtained using electrical impedance tomography. Since computation of the ventilation-perfusion index only requires knowledge of the internal conductivity, any conductivity reconstruction method may be used. The method is explained and results are presented using conductivities obtained from two EIT systems, one using an iterative method and the other a linearization method.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Volume fraction of blood ranging from 0 (lightest) to 1 (darkest), with frame rate 18.8 fps using ACT 3 data
Figure 2
Figure 2
Volume fraction of air ranging from 0 (lightest) to 1 (darkest), with frame rate 18.8 fps using ACT 3 data
Figure 3
Figure 3
Typical volume fraction waveforms for a lung voxel during ventilation and perfusion, with a frame rate of 18.8 fps using ACT 3 data
Figure 4
Figure 4
Ventilation-perfusion index maps from ACT 3 data

References

    1. Amm B, Kao T-J, Wang X, Boverman G, Shoudy D, Sabatini J, Ashe JM, Newell JC, Isaacson D, Saulnier GJ, Davenport D. Real-Time 3D Electrical Impedance Imaging for Ventilation Monitoring of the lung: Pilot study. IEEE EMBC 36th Conf; Chicago. 2014. - PubMed
    1. Ashe JM, Shoudy D, Boverman G, Sabatini J, Kao T-J, Amm B. A High Precision Parallel Current Drive Experimental EIT System. 15th Int. Conf. Biomed. Appl. EIT; 2014. pp. 24–26.
    1. Blue RS, Isaacson D, Newell JC. Real-time three dimensional electrical impedance imaging. Physiol Meas. 2000;21:1–12. - PubMed
    1. Borcea L. Electrical impedance tomography. Inverse Problems. 2002;18:R99–R136. - PMC - PubMed
    1. Borges JB, Suarez-Sipmann F, Bohm SH, Tusman G, Melo A, Maripuu E, Sandström M, Park M, Costa ELV, Hedenstierna G, Amato M. Regional lung perfusion estimated by electrical impedance tomography in a piglet model of lung collapse. J Appl Physiol. 2012;112:225–236. - PubMed

Publication types

LinkOut - more resources