Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2015 Jun;166(6):1337-41.
doi: 10.1016/j.jpeds.2015.03.042.

New challenges in the diagnosis and management of cystic fibrosis

Hara Levy  1 , Philip M Farrell  2
Affiliations
Editorial

New challenges in the diagnosis and management of cystic fibrosis

Hara Levy et al. J Pediatr. 2015 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure
Figure
Clinical descriptors capture the overlaps and distinctions among CF, CFTR, and CRMS. CFSPID and delayed CF could overlap CF and/or CFTR-RD and lead to a “phase shift,” as described in the text, or be completely distinct entities. PI, pancreatic insufficient; PS, pancreatic sufficient.
See this image and copyright information in PMC

Comment on

References

    1. Farrell PM, Rosenstein BJ, White TB, Accurso FJ, Castellani C, Cutting GR, et al. Guidelines for diagnosis of cystic fibrosis in newborns through older adults: Cystic Fibrosis Foundation consensus report. J Pediatr. 2008;153:S4–14. - PMC - PubMed
    1. Borowitz D, Parad RB, Sharp JK, Sabadosa K, Robinson KA, Rock M, et al. Cystic Fibrosis Foundation practice guidelines for the management of infants with cystic fibrosis transmembrane conductance regulator-related metabolic syndrome during the first two years of life and beyond. J Pediatr. 2009;155:S106–16. - PMC - PubMed
    1. Munck A, Mayell SJ, Winters V, Shawcross A, Derichs N, Parad R, et al. Cystic fibrosis screen positive, inconclusive diagnosis (CFSPID): a new designation and management recommendations for infants with an inconclusive diagnosis following newborn screening. J Cyst Fibros. 2015 in press. - PubMed
    1. Bombieri C, Claustres M, De Boeck K, Derichs N, Dodge J, Girodon E, et al. Recommendations for the classification of diseases as CFTR-related disorders. J Cyst Fibros. 2011;10(Suppl 2):S86–102. - PubMed
    1. Sosnay PR, Siklosi KR, Van Goor F, Kaniecki K, Yu H, Sharma N, et al. Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene. Nat Genet. 2013;45:1160–7. - PMC - PubMed