Overdiagnosis of bone fragility in the quest to prevent hip fracture

Affiliations

¹ Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
² Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden.
³ Department of Hand Surgery, Tampere University Hospital, Tampere, Finland.
⁴ Centre for Statistics in Medicine, Botnar Research Centre, University of Oxford, Oxford, UK.
⁵ Departments of Anesthesiology, Pharmacology, and Therapeutics and Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
⁶ Faculty of Pharmacy and Charles Perkins Centre, University of Sydney, Sydney, Australia.
⁷ Drug Information Unit, Navarre Regional Health Service, Pamplona, Navarre, Spain.
⁸ Department of Health, Government of Navarre, Pamplona, Navarre, Spain.
⁹ UKK Institute for Health Promotion Research, Tampere, Finland.

Teppo L N Järvinen et al. BMJ. 2015.

. 2015 May 26:350:h2088.

doi: 10.1136/bmj.h2088.

¹ Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.
² Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden.
³ Department of Hand Surgery, Tampere University Hospital, Tampere, Finland.
⁴ Centre for Statistics in Medicine, Botnar Research Centre, University of Oxford, Oxford, UK.
⁵ Departments of Anesthesiology, Pharmacology, and Therapeutics and Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
⁶ Faculty of Pharmacy and Charles Perkins Centre, University of Sydney, Sydney, Australia.
⁷ Drug Information Unit, Navarre Regional Health Service, Pamplona, Navarre, Spain.
⁸ Department of Health, Government of Navarre, Pamplona, Navarre, Spain.
⁹ UKK Institute for Health Promotion Research, Tampere, Finland.

No abstract available

Comment in

Overdiagnosis of osteoporosis: fact or fallacy?
Compston J. Compston J. Osteoporos Int. 2015 Aug;26(8):2051-4. doi: 10.1007/s00198-015-3220-0. Epub 2015 Jul 2. Osteoporos Int. 2015. PMID: 26134683 No abstract available.
Treatment of osteoporosis is not futile.
Lee DB, Adler RA, Gagel RF. Lee DB, et al. BMJ. 2015 Jul 14;351:h3274. doi: 10.1136/bmj.h3274. BMJ. 2015. PMID: 26174815 No abstract available.
Authors' reply to Lee and colleagues.
Järvinen T, Michaëlsson K, Jokihaara J, Collins GS, Perry TL, Mintzes B, Musini V, Erviti J, Gorricho J, Wright JM, Sievänen H. Järvinen T, et al. BMJ. 2015 Jul 14;351:h3737. doi: 10.1136/bmj.h3737. BMJ. 2015. PMID: 26174986 No abstract available.
Both falling and bone fragility should be targeted to prevent hip fracture in older adults.
Sugiyama T, Kim YT, Oda H. Sugiyama T, et al. Osteoporos Int. 2016 Mar;27(3):1277-1278. doi: 10.1007/s00198-015-3373-x. Epub 2015 Oct 22. Osteoporos Int. 2016. PMID: 26493813 No abstract available.
The real enemy is fragility fracture, not osteoporosis.
Uzoigwe CE. Uzoigwe CE. Osteoporos Int. 2016 Jan;27(1):413-5. doi: 10.1007/s00198-015-3405-6. Epub 2015 Nov 13. Osteoporos Int. 2016. PMID: 26564226 No abstract available.
A BMD threshold for treatment efficacy in osteoporosis? A need to consider the whole evidence base.
McCloskey E. McCloskey E. Osteoporos Int. 2016 Jan;27(1):417-9. doi: 10.1007/s00198-015-3406-5. Epub 2015 Nov 13. Osteoporos Int. 2016. PMID: 26564227 No abstract available.