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Comment
. 2015 May 27;16(1):109.
doi: 10.1186/s13059-015-0673-6.

Is mouse embryonic stem cell technology obsolete?

William C Skarnes  1
Affiliations
Comment

Is mouse embryonic stem cell technology obsolete?

William C Skarnes. Genome Biol. .

Abstract

Injection of recombinant Cas9 protein and synthetic guide RNAs into mouse zygotes has been shown to facilitate gene disruption and knock-ins using the CRISPR system. These technologies may soon displace genetic modification using embryonic stem cells.

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References

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