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. 2015 Nov;19(4):685-93.
doi: 10.1007/s11030-015-9605-3. Epub 2015 May 28.

Iodine-catalyzed sp³ C-H bond activation by selenium dioxide: synthesis of diindolylmethanes and di(3-indolyl)selanides

P Seetham Naidu  1 , Swarup Majumder  1 , Pulak J Bhuyan  2
Affiliations

Iodine-catalyzed sp³ C-H bond activation by selenium dioxide: synthesis of diindolylmethanes and di(3-indolyl)selanides

P Seetham Naidu et al. Mol Divers. 2015 Nov.

Abstract

An efficient reaction protocol was developed for the synthesis of several diindolylmethane derivatives via the [Formula: see text] C-H bond activation of aryl methyl ketones by [Formula: see text] and indoles in the presence of catalytic amounts of [Formula: see text] at 80 [Formula: see text] using dioxane as solvent. Unexpectedly, an interesting class of di(3-indolyl)selenide compounds was isolated when the reaction was carried out at room temperature.

Keywords: C–H activation; Diindolylmethanes; Indole; Indolylselanides; Iodine; Selanides.

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