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Review
. 2015 May 21;21(19):5805-12.
doi: 10.3748/wjg.v21.i19.5805.

Incidence and treatment of brain metastasis in patients with esophageal carcinoma

Wei Feng  1 , Peng Zhang  1 , Xiao Zheng  1 , Ming Chen  1 , Wei-Min Mao  1
Affiliations
Review

Incidence and treatment of brain metastasis in patients with esophageal carcinoma

Wei Feng et al. World J Gastroenterol. .

Abstract

Brain metastasis from esophageal carcinoma (BMEC) is very rare, but its incidence has increased in the United States, Japan, China and other counties. Reports on BMEC have largely been focused on examining whether adjuvant therapy for esophageal cancer influences the survival duration of BMEC patients and on the imaging characteristics of BMEC determined using new medical equipment. The difference between different pathological types of esophageal cancer, especially adenocarcinoma and squamous cell carcinoma, is one important factor used to assess the influence of BMEC. Adjuvant therapy, including radiotherapy and chemotherapy, for esophageal cancer with different characteristics in different countries may affect BMEC treatment outcomes. The degree of popularization of advanced medical equipment is a major concern related to the prevalence of BMEC. Furthermore, targeted BMEC treatment is under development in developed countries. In this article, we reviewed the debate surrounding BMEC and analyzed BMEC studies from different perspectives.

Keywords: Brain metastasis; Computed tomography; Esophageal carcinoma; Magnetic resonance imagin.

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References

    1. Gaspar L, Scott C, Rotman M, Asbell S, Phillips T, Wasserman T, McKenna WG, Byhardt R. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys. 1997;37:745–751. - PubMed
    1. Farnell GF, Buckner JC, Cascino TL, O’Connell MJ, Schomberg PJ, Suman V. Brain metastases from colorectal carcinoma. The long term survivors. Cancer. 1996;78:711–716. - PubMed
    1. Tasdemiroglu E, Kaya AH, Bek S, Emir CB, Sengoz A, Kilickesmez O. Neurologic complications of cancer part 1: central nervous system metastasis. Neurosurg Quart. 2004;14:71–83.
    1. Bartelt S, Momm F, Weissenberger C, Lutterbach J. Patients with brain metastases from gastrointestinal tract cancer treated with whole brain radiation therapy: prognostic factors and survival. World J Gastroenterol. 2004;10:3345–3348. - PMC - PubMed
    1. Pohl H, Welch HG. The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst. 2005;97:142–146. - PubMed

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