Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Jun;17(6):707-9.
doi: 10.1038/ncb3178.

Gut healing: haemocytes aid via Sax and Tkv jazzes it down

Lesley N Weaver  1 , Daniela Drummond-Barbosa  2
Affiliations
Comment

Gut healing: haemocytes aid via Sax and Tkv jazzes it down

Lesley N Weaver et al. Nat Cell Biol. 2015 Jun.

Abstract

Control of stem cell activity is essential for accurate regeneration. Pathogen- or chemical-induced intestinal damage is now shown to recruit haemocytes expressing bone morphogenetic protein signals that stimulate proliferation of intestinal stem cells and subsequently induce their quiescence, in conjunction with muscle-derived bone morphogenetic proteins. A temporal switch in expression of Type I receptors enables this two-phase response.

PubMed Disclaimer

Comment on

References

    1. Development. 2006 Sep;133(17):3295-303 - PubMed
    1. Aging Cell. 2008 Aug;7(4):590-8 - PubMed
    1. J Cell Biol. 2013 Jun 10;201(6):945-61 - PubMed
    1. BMC Biol. 2010 Dec 22;8:152 - PubMed
    1. Wiley Interdiscip Rev Dev Biol. 2012 Sep-Oct;1(5):657-74 - PubMed

LinkOut - more resources