Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jul 1;2(3):32.
eCollection 2013 Jul-Sep.

Management of Duodenal Atresia in the setting of Congenital Leukemia with Massive Hepatomegaly

Sathyaprasad C Burjonrappa  1
Affiliations
Case Reports

Management of Duodenal Atresia in the setting of Congenital Leukemia with Massive Hepatomegaly

Sathyaprasad C Burjonrappa. J Neonatal Surg. .

Abstract

Down's syndrome (DS) is associated with duodenal atresia (DA) in about 8-10% of cases. Transient Myeloproliferative Disorder (TMD)/Acute Myeloid Leukemia (AML) is also associated with the trisomy 21 mutation. The occurrence of the two conditions together complicates the diagnosis and surgical management of the DA. We discuss the technical aspects of management of the DA in this clinical setting.

Keywords: Down's syndrome; Duodenal atresia; Transient myeloproliferative disorder.

PubMed Disclaimer

References

    1. Choudhry MS, Rahman N, Boyd P, Lakhoo K. Duodenal atresia: associated anomalies, prenatal diagnosis and outcome. Pediatr Surg Int. 2009; 25:727-30. - PubMed
    1. Freeman S, Taft L, Dooley K, Allran K, Sherman SL, Hassold TJ. Population-based study of congenital heart defects in Down syndrome. Am J Med Genet. 1998; 80:213-7. - PubMed
    1. Moiz B, Shafiq M. Transient myeloproliferative disorder. Blood. 2012; 120: 4672. - PubMed
    1. Gamis AS, Alonzo TA, Gerbing RB, Hilden JM, Sorrell AD, Sharma M, et al. Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the children’s oncology group study A2971. Blood. 2011; 118: 6752-9. - PMC - PubMed
    1. Zipursky A, Brown E, Christensen H, Sutherland R, Doyle J. Leukemia and/or myeloproliferative syndrome in neonates with Down syndrome. Semin Perinatol. 1997; 21:97-101. - PubMed

Publication types

LinkOut - more resources