Analysis of personal and family factors in the persistence of attention deficit hyperactivity disorder: results of a prospective follow-up study in childhood
- PMID: 26024216
- PMCID: PMC4449179
- DOI: 10.1371/journal.pone.0128325
Analysis of personal and family factors in the persistence of attention deficit hyperactivity disorder: results of a prospective follow-up study in childhood
Abstract
Objectives: To study the course of ADHD during childhood and analyze possible personal and family predictor variables of the results.
Method: Sixty-one children with ADHD who were between 6 and 12 years old at the baseline assessment were evaluated 30 months later (mean age at baseline: 8.70 ± 1.97; mean age at follow-up: 10.98 ± 2.19). Status of ADHD in follow-up was identified as persistent (met DSM-IV-TR criteria according to parents' and teachers' ratings), contextually persistent (met ADHD criteria according to one informant, and there was functional impairment) and remitted ADHD (with subthreshold clinical symptomatology). Associated psychological disorders of the three groups were analyzed in the follow-up with the Conners' Rating Scales. The groups were compared on ADHD characteristics (symptoms of ADHD and impairment), child psychopathology, executive functioning (EF; inhibition, working memory) and parenting characteristics (parental stress and discipline styles) at baseline.
Results: At the follow-up, 55.7% of the children continued to meet the DSM-IV-TR criteria for ADHD, 29.5% showed contextual persistence, and 14.8% presented remission of the disorder. The persistent and contextually persistent ADHD groups showed more associated psychological disorders. Inattention, oppositional problems, cognitive problems and impairment at baseline distinguished the remitted ADHD children from the persistent and contextually persistent ADHD children. Moreover, the persistent groups had significantly more emotional liability and higher parental stress than the group in remission, while no differences in EF where found among the groups.
Conclusions: ADHD children continue to present symptoms, as well as comorbid psychological problems, during adolescence and early adulthood. These findings confirm that persistence of ADHD is associated with child psychopathology, parental stress and impairment in childhood.
Conflict of interest statement
Figures

Similar articles
-
Childhood Factors Affecting Persistence and Desistence of Attention-Deficit/Hyperactivity Disorder Symptoms in Adulthood: Results From the MTA.J Am Acad Child Adolesc Psychiatry. 2016 Nov;55(11):937-944.e4. doi: 10.1016/j.jaac.2016.05.027. Epub 2016 Sep 2. J Am Acad Child Adolesc Psychiatry. 2016. PMID: 27806861 Free PMC article.
-
Evaluation of the Persistence, Remission, and Emergence of Attention-Deficit/Hyperactivity Disorder in Young Adulthood.JAMA Psychiatry. 2016 Jul 1;73(7):713-20. doi: 10.1001/jamapsychiatry.2016.0465. JAMA Psychiatry. 2016. PMID: 27192174 Free PMC article.
-
A 6-year follow-up of a large European cohort of children with attention-deficit/hyperactivity disorder-combined subtype: outcomes in late adolescence and young adulthood.Eur Child Adolesc Psychiatry. 2016 Sep;25(9):1007-17. doi: 10.1007/s00787-016-0820-y. Epub 2016 Feb 2. Eur Child Adolesc Psychiatry. 2016. PMID: 26837866 Free PMC article.
-
[The course of attention deficit hyperactivity disorder (ADHD) over the life span].Psychiatriki. 2012 Jun;23 Suppl 1:49-59. Psychiatriki. 2012. PMID: 22796973 Review. Greek, Modern.
-
The cognitive-energetic model: an empirical approach to attention-deficit hyperactivity disorder.Neurosci Biobehav Rev. 2000 Jan;24(1):7-12. doi: 10.1016/s0149-7634(99)00060-3. Neurosci Biobehav Rev. 2000. PMID: 10654654 Review.
Cited by
-
Empirical examination of executive functioning, ADHD associated behaviors, and functional impairments in adults with persistent ADHD, remittent ADHD, and without ADHD.BMC Psychiatry. 2020 Mar 24;20(1):134. doi: 10.1186/s12888-020-02542-y. BMC Psychiatry. 2020. PMID: 32204708 Free PMC article.
-
Childhood Factors Affecting Persistence and Desistence of Attention-Deficit/Hyperactivity Disorder Symptoms in Adulthood: Results From the MTA.J Am Acad Child Adolesc Psychiatry. 2016 Nov;55(11):937-944.e4. doi: 10.1016/j.jaac.2016.05.027. Epub 2016 Sep 2. J Am Acad Child Adolesc Psychiatry. 2016. PMID: 27806861 Free PMC article.
-
Assessment of hyperactivity-impulsivity and attention deficit in adolescents by self-report and its association with psychopathology and academic performance.Front Psychol. 2022 Aug 18;13:989610. doi: 10.3389/fpsyg.2022.989610. eCollection 2022. Front Psychol. 2022. PMID: 36059738 Free PMC article.
-
ADHD symptoms across adolescence: the role of the family and school climate and the DRD4 and 5-HTTLPR genotype.Eur Child Adolesc Psychiatry. 2020 Aug;29(8):1049-1061. doi: 10.1007/s00787-019-01424-3. Epub 2019 Oct 18. Eur Child Adolesc Psychiatry. 2020. PMID: 31628528 Free PMC article.
References
Publication types
MeSH terms
Associated data
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous