[Pulmonary and muscular localization of Wegener's granulomatosis. Apropos of a case]

Abstract

The authors report their observations on a patient presenting with Wegener's granulomatosis with initially isolated pulmonary involvement. Following treatment with a combination of steroid therapy and immunosuppressives muscular involvement developed with specific histological changes. The disease was only controlled by substituting at the same dose prednisone for the methylsulphobenzoate of prednisolone which was prescribed initially; this suggests in equivalent doses the superiority of one product over the other was achieved by a different pharmacodynamic behaviour.