ADAMTS-5 takes centre stage in new developments for aggrecanase inhibitors

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Editorial

A J Fosang. Osteoarthritis Cartilage. 2015 Aug.

Free article

. 2015 Aug;23(8):1231-2.

doi: 10.1016/j.joca.2015.05.023. Epub 2015 May 28.

¹ University of Melbourne, Murdoch Childrens Research Institute, Parkville, Vic 3052, Australia. Electronic address: amanda.fosang@mcri.edu.au.

No abstract available

Keywords: ADAMTS-5; ADAMTS-5 inhibitor; Aggrecan; Aggrecanase; DMOAD; Disease-modifying OA drugs.

Comment on

Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.
Larkin J, Lohr TA, Elefante L, Shearin J, Matico R, Su JL, Xue Y, Liu F, Genell C, Miller RE, Tran PB, Malfait AM, Maier CC, Matheny CJ. Larkin J, et al. Osteoarthritis Cartilage. 2015 Aug;23(8):1254-66. doi: 10.1016/j.joca.2015.02.778. Epub 2015 Mar 20. Osteoarthritis Cartilage. 2015. PMID: 25800415 Free PMC article.