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Comment
. 2015 Aug;25(8):887-8.
doi: 10.1038/cr.2015.66. Epub 2015 Jun 2.

Cancer immunotherapy: exploiting neoepitopes

Michael Platten  1 , Rienk Offringa  2
Affiliations
Comment

Cancer immunotherapy: exploiting neoepitopes

Michael Platten et al. Cell Res. 2015 Aug.

Abstract

The efficacy of cancer vaccines has long been hampered by insufficient definition of tumor-specific antigens. A recent study by Kreiter et al. published in Nature has provided a blueprint for a patient-tailored approach to develop individualized RNA vaccines.

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Comment on

  • Mutant MHC class II epitopes drive therapeutic immune responses to cancer.
    Kreiter S, Vormehr M, van de Roemer N, Diken M, Löwer M, Diekmann J, Boegel S, Schrörs B, Vascotto F, Castle JC, Tadmor AD, Schoenberger SP, Huber C, Türeci Ö, Sahin U. Kreiter S, et al. Nature. 2015 Apr 30;520(7549):692-6. doi: 10.1038/nature14426. Epub 2015 Apr 22. Nature. 2015. PMID: 25901682 Free PMC article.

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