Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Feb 4;2(1):ofv004.
doi: 10.1093/ofid/ofv004. eCollection 2015 Jan.

Weight gain after fecal microbiota transplantation

Neha Alang  1 , Colleen R Kelly  2
Affiliations

Weight gain after fecal microbiota transplantation

Neha Alang et al. Open Forum Infect Dis. .

Abstract

Fecal microbiota transplantation (FMT) is a promising treatment for recurrent Clostridium difficile infection. We report a case of a woman successfully treated with FMT who developed new-onset obesity after receiving stool from a healthy but overweight donor. This case may stimulate further studies on the mechanisms of the nutritional-neural-microbiota axis and reports of outcomes in patients who have used nonideal donors for FMT.

Keywords: Clostridium difficile infection; fecal microbiota transplantation; gut microbiota; obesity.

PubMed Disclaimer

Comment in

References

    1. Lender N, Talley NJ, Enck P, et al. Review article: Associations between Helicobacter pylori and obesity–an ecological study. Aliment Pharmacol Ther. 2014;40:24–31. - PubMed
    1. Ridaura VK, Faith JJ, Rey FE, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science. 2013 doi:10.1126/science.1241214. - DOI - PMC - PubMed
    1. Youngster I, Sauk J, Pindar C, et al. Fecal microbiota transplant for relapsing Clostridium difficile infection using a frozen inoculum from unrelated donors: a randomized, open-label, controlled pilot study. Clin Infect Dis. 2014;58:1515–22. - PMC - PubMed