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Review
. 2015 Jun;44(2):411-34.
doi: 10.1016/j.ecl.2015.03.001.

Adrenocortical carcinoma

Eric Baudin  1 ; Endocrine Tumor Board of Gustave Roussy
Collaborators, Affiliations
Review

Adrenocortical carcinoma

Eric Baudin et al. Endocrinol Metab Clin North Am. 2015 Jun.

Erratum in

  • Endocrinol Metab Clin North Am. 2015 Sep;44(3):xix. multiple investigator names added

Abstract

Recent developments in the treatment of adrenocortical carcinoma (ACC) include diagnostic and prognostic risk stratification algorithms, increasing evidence of the impact of historical therapies on overall survival, and emerging targets from integrated epigenomic and genomic analyses. Advances include proper clinical and molecular characterization of all patients with ACC, standardization of proliferative index analyses, referral of these patients to large cancer referral centers at the time of first surgery, and development of new trials in patients with well-characterized ACC. Networking and progress in the molecular characterization of ACC constitute the basis for significant future therapeutic breakthroughs.

Keywords: Adrenocortical carcinoma; Chemotherapy; Metastasis; Mitotane; Predictors; Prognosis; Surrogate; Survival.

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