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Comment
. 2015 Jun 16;112(24):7345-6.
doi: 10.1073/pnas.1507916112. Epub 2015 Jun 2.

Measuring ruggedness in fitness landscapes

Jeremy Van Cleve  1 , Daniel B Weissman  2
Affiliations
Comment

Measuring ruggedness in fitness landscapes

Jeremy Van Cleve et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Fitness landscapes. The horizontal axes represent the space of different combinations of genotypes, and the vertical axis is individual fitness as a function of genotype. (A) Smooth fitness landscape with a single peak and no fitness interactions among genes. Different evolutionary trajectories lead to the same peak. (B) Rugged fitness landscape with multiple peaks and pervasive interactions among genes. Different evolutionary trajectories can reach different peaks even from the same initial genotype. The blue highlighted region shows that each peak in the rugged landscape still looks like a smooth, single-peaked landscape locally.
See this image and copyright information in PMC

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References

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