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Review
. 2015 Jun 2;13(6):3479-513.
doi: 10.3390/md13063479.

Antibacterial and antifungal compounds from marine fungi

Lijian Xu  1 , Wei Meng  2 , Cong Cao  3 , Jian Wang  4 , Wenjun Shan  5 , Qinggui Wang  6
Affiliations
Review

Antibacterial and antifungal compounds from marine fungi

Lijian Xu et al. Mar Drugs. .

Abstract

This paper reviews 116 new compounds with antifungal or antibacterial activities as well as 169 other known antimicrobial compounds, with a specific focus on January 2010 through March 2015. Furthermore, the phylogeny of the fungi producing these antibacterial or antifungal compounds was analyzed. The new methods used to isolate marine fungi that possess antibacterial or antifungal activities as well as the relationship between structure and activity are shown in this review.

Keywords: Aspergillus; antibacterial; antibiotic; antifungal; antimicrobial; marine fungus; metabolites; polyketide.

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Figures

Figure 1
Figure 1
The approximate location of material collections for fungal isolation.
Figure 2
Figure 2
Numbers of fungal strains from different isolation materials.
Figure 3
Figure 3
Phylogenetic analysis of marine fungi produced antibacterial or antifungal compounds.
Figure 4
Figure 4
Structures of compound 1–6.
Figure 5
Figure 5
Structures of compound 7–13 (the red moiety enhances the antimicrobial activity).
Figure 6
Figure 6
Structures of compound 14–18 (the red moiety enhances the antimicrobial activity).
Figure 7
Figure 7
Structures of compound 19–23 (the red moiety enhances the antimicrobial activity).
Figure 8
Figure 8
Structures of compound 24–30 (the red moiety enhances the antimicrobial activity).
Figure 9
Figure 9
Structures of compound 31–39 (the red moiety enhances the antimicrobial activity).
Figure 10
Figure 10
Structures of compound 40–42 (the red moiety enhances the antimicrobial activity).
Figure 11
Figure 11
Structures of compound 43–48 (the red moiety enhances the antimicrobial activity).
Figure 12
Figure 12
Structures of compound 49–52.
Figure 13
Figure 13
Structures of compound 53–58 (the red moiety enhances the antimicrobial activity).
Figure 14
Figure 14
Structures of compound 59–61 (the red moiety enhances the antimicrobial activity).
Figure 15
Figure 15
Structures of compound 62–65 (the red moiety enhances the antimicrobial activity).
Figure 16
Figure 16
Structures of compound 66–71 (the red moiety enhances the antimicrobial activity).
Figure 17
Figure 17
Structures of compound 72–76.
Figure 18
Figure 18
Structures of compound 77–84 (the red moiety enhances the antimicrobial activity).
Figure 19
Figure 19
Structures of compound 85–89 (the red moiety enhances the antimicrobial activity).
Figure 20
Figure 20
Structures of compound 90–93 (the red moiety enhances the antimicrobial activity).
Figure 21
Figure 21
Structures of compound 94–95 (the red moiety enhances the antimicrobial activity).
Figure 22
Figure 22
Structures of compound 96–101.
Figure 23
Figure 23
Structures of compound 102–105 (the red moiety enhances the antimicrobial activity).
Figure 24
Figure 24
Structures of compound 106–111 (the red moiety enhances the antimicrobial activity).
Figure 25
Figure 25
Structures of compound 112–116.
See this image and copyright information in PMC

References

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