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Clinical Trial
. 2015 Jun 4;125(23):3668-9.
doi: 10.1182/blood-2015-03-635391.

Phase 1/2 trial of vorinostat in patients with sickle cell disease who have not benefitted from hydroxyurea

Affiliations
Clinical Trial

Phase 1/2 trial of vorinostat in patients with sickle cell disease who have not benefitted from hydroxyurea

Maureen M Okam et al. Blood. .
No abstract available

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References

    1. Brousseau DC, Panepinto JA, Nimmer M, Hoffmann RG. The number of people with sickle-cell disease in the United States: national and state estimates. Am J Hematol. 2010;85(1):77–78. - PubMed
    1. Akinsheye I, Alsultan A, Solovieff N, et al. Fetal hemoglobin in sickle cell anemia. Blood. 2011;118(1):19–27. - PMC - PubMed
    1. Charache S, Terrin ML, Moore RD, et al. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med. 1995;332(20):1317–1322. - PubMed
    1. Wang WC, Ware RE, Miller ST, et al. BABY HUG investigators. Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG). Lancet. 2011;377(9778):1663–1672. - PMC - PubMed
    1. Cao H, Stamatoyannopoulos G, Jung M. Induction of human gamma globin gene expression by histone deacetylase inhibitors. Blood. 2004;103(2):701–709. - PMC - PubMed

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