Inflammatory epidermolysis bullosa acquisita in a 4-year-old girl

Abstract

This study presents a case of linear immunoglobulin A dermatosis-like epidermolysis bullosa acquisita in a 4-year-old girl showing rapid, widespread and inflammatory skin lesions. The diagnosis was confirmed by histopathology, direct and indirect immunofluorescence, various immunoblotting analyses and enzyme-linked immunosorbent assays. Despite the severe clinical manifestations, the disease was successfully controlled by combination therapy of oral prednisolone and dapsone.

Keywords: acquired epidermolysis bullosa; bullous skin disease; childhood blistering; epidermolysis bullosa aquisita antigen; inflammatory epidermolysis bullosa aquisita.