Gear Up in Circles
- PMID: 26046645
- DOI: 10.1016/j.molcel.2015.05.027
Gear Up in Circles
Abstract
Two studies published in this issue of Molecular Cell (Rybak-Wolf et al., 2015) and in the April issue of Nature Neuroscience (You et al., 2015) independently report the upregulated expression of back-spliced circular RNAs (circRNAs) in brains and suggest that they have a potential to regulate synaptic function.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.Nat Neurosci. 2015 Apr;18(4):603-610. doi: 10.1038/nn.3975. Epub 2015 Feb 25. Nat Neurosci. 2015. PMID: 25714049 Free PMC article.
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Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.Mol Cell. 2015 Jun 4;58(5):870-85. doi: 10.1016/j.molcel.2015.03.027. Epub 2015 Apr 23. Mol Cell. 2015. PMID: 25921068
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