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. 2015 Jun 4;16(6):574-5.
doi: 10.1016/j.stem.2015.05.001.

Bringing Blood Stem Cell Phenotype, Genotype, and Function Closer Together

Wenlian Qiao  1 , Peter W Zandstra  2
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Bringing Blood Stem Cell Phenotype, Genotype, and Function Closer Together

Wenlian Qiao et al. Cell Stem Cell. .
Free article

Abstract

Imperfect purity, subtypes, and retrospective functional assays compromise efforts to define the molecular identity of hematopoietic stem cells (HSCs). In this issue of Cell Stem Cell, Wilson et al. (2015) use a single-cell-based bioinformatics-experimental strategy to extract a consensus molecular signature from heterogeneous HSC pools. Their data and strategy provide a powerful resource for stem cell characterization.

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