[Clinical experiences with nalbuphine]

Abstract

The analgesic nalbuphine was tested in Czechoslovakia in three departments of anaesthesiology. On 94 patients during the first 24 postoperative hours 43.3% of the patients were sufficiently treated with one injection of 10 mg nalbuphine, 30% needed two injections, 20% three injections and 6.7% four injections. The average duration of the analgesic effect was about 4 hours. Repeated injections achieved prolonged action. Side-effects occurred less frequently with nalbuphine than with morphine. It was shown that it is important in the postoperative period to start with the analgetic therapy before pain occurs.