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. 2015 Oct 1;70(2):212-7.
doi: 10.1097/QAI.0000000000000715.

Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial

Jennifer E Balkus  1 , Gonasagrie Nair, Elizabeth T Montgomery, Anu Mishra, Thesla Palanee-Phillips, Gita Ramjee, Ravindre Panchia, Pearl Selepe, Barbra A Richardson, Zvavahera M Chirenje, Jeanne M Marrazzo
Affiliations

Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial

Jennifer E Balkus et al. J Acquir Immune Defic Syndr. .

Abstract

A recent analysis from South Africa reported no association between age-disparate relationships and HIV-1 acquisition. We assessed the association between male partner age and HIV-1 acquisition among South African women participating in the VOICE trial. Of 4077 women enrolled, 3789 had complete data; 26% and 5% reported having a partner >5 and >10 years older at enrollment, respectively. Reporting a partner >5 years older (hazard ratio = 1.00; 95% confidence interval: 0.74 to 1.35) or >10 older (hazard ratio = 0.92; 95% confidence interval: 0.49 to 1.74) was not associated with HIV-1 acquisition. These data corroborate recent reports and may suggest a shift in local epidemiology of heterosexual HIV-1 transmission.

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Conflict of interest statement

Potential Conflicts of Interest: All authors declare no commercial or other associations that might pose a conflict of interest relevant to the submitted work.

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